SCHEMBL8034614

SCHEMBL8034614

C[Si](C)(C)C1([Ti](Cl)(Cl)Cl)C=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OXTR P30559 1/20 0.32
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10318428 0.83
SCHEMBL10318272 0.83
SCHEMBL10317049 0.79
SCHEMBL10320527 0.79 OXTR (0.32) OXTR
SCHEMBL10319327 0.79 OXTR (0.32) OXTR
SCHEMBL10319434 0.77
SCHEMBL10317746 0.77 OXTR (0.33) OXTR
SCHEMBL6342811 0.76 OXTR (0.34) OXTRHSD11B1
SCHEMBL11897427 0.75
SCHEMBL10318052 0.75 OXTR (0.32) OXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0796875-B1 Process for the preparation of crystalline vinylaromatic polymers with a predominant syndiotactic structure ENICHEM SPA (IT) 2000-03-29 EP disclosed
US-5721327-A Process for the preparation of crystalline vinylaromatic polymers with a predominant syndiotactic structure ENICHEM S.P.A. (IT) 1998-02-24 US disclosed
EP-0796875-A2 Process for the preparation of crystalline vinylaromatic polymers with a predominant syndiotactic structure ENICHEM S.p.A. (IT) 1997-09-24 EP disclosed