Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024898 | 0.91 | MAPT (0.40) | ATMNAMPTHPGDMEN1ALDH1A1 | |
| SCHEMBL8036259 | 0.89 | NR1H4 (0.39) | NR1H4ATMNAMPTALDH1A1LMNA | |
| SCHEMBL8027574 | 0.88 | NAMPT (0.39) | ATMNAMPTHPGDMEN1ALDH1A1 | |
| SCHEMBL8031087 | 0.87 | ATM (0.51) | ATMNAMPTHPGDMEN1ALDH1A1 | |
| SCHEMBL4009392 | 0.86 | CNR1 (0.40) | ATMNAMPTDPP4 | |
| SCHEMBL8031033 | 0.86 | KDM4E (0.48) | NR1H4ATMHPGDMEN1ALDH1A1 | |
| SCHEMBL4007857 | 0.82 | FABP3 (0.45) | NAMPTHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL4009791 | 0.81 | FABP4 (0.41) | NR1H4ATMNAMPTHPGDPTGER1 | |
| SCHEMBL8024878 | 0.80 | NAMPT (0.40) | NAMPTHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL8037630 | 0.78 | NAMPT (0.40) | ATMNAMPTHPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |