SCHEMBL8034671

SCHEMBL8034671

CN1CCc2c(c3cc(C(Br)N4CCc5c(c6cc(F)ccc6n5CCc5ccccn5)C4)ccc3n2CCc2ccccn2)C1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 17/20 0.80
HRH1 P35367 15/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12881966 0.89 HTR6 (1.00) HTR6HRH1
Hydrochloric Acid SCHEMBL21195012 0.89 HTR6 (0.98) HTR6HRH1
SCHEMBL8036723 0.84 HTR6 (0.89) HTR6HRH1
SCHEMBL8034735 0.81 HTR6 (0.83) HTR6HRH1
SCHEMBL12881963 0.80 HTR6 (1.00) HTR6HRH1
SCHEMBL3716617 0.79 HTR6 (1.00) HTR6HRH1
SCHEMBL3712759 0.79 HTR6 (1.00) HTR6HRH1
SCHEMBL3717277 0.78 HTR6 (0.79) HTR6HRH1
SCHEMBL8038601 0.78 HTR6 (0.79) HTR6HRH1
SCHEMBL12881967 0.78 HTR6 (1.00) HTR6HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009082268-A2 LIGANDS OF α-ADRENOCEPTORS AND OF DOPAMINE, HISTAMINE, IMIDAZOLINE AND SEROTONIN RECEPTORS AND THE USE THEREOF ALLA CHEM, LLC (US) 2009-07-02 WO disclosed