Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043928 | 0.90 | EDNRA (0.51) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8034743 | 0.87 | EDNRA (0.63) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8035062 | 0.79 | EDNRA (0.45) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7496855 | 0.78 | EDNRA (0.47) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8043916 | 0.77 | EDNRA (0.75) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7496887 | 0.77 | EDNRA (0.46) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3835438 | 0.76 | EDNRA (0.69) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8434773 | 0.76 | EDNRA (0.47) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8415160 | 0.75 | EDNRA (0.46) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8663507 | 0.74 | KDM4E (0.50) | EDNRAALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143774-A | DRUGS AS HYPOTENSIVE AGENTS | HOECHST MARION ROUSSEL (FR) | 2000-11-07 | — | — | US | disclosed |