Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.63 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835438 | 0.90 | EDNRA (0.69) | EDNRAAGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL8034740 | 0.87 | EDNRA (0.46) | EDNRAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3834405 | 0.82 | EDNRA (0.81) | EDNRAAGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL3837125 | 0.80 | EDNRA (0.70) | EDNRAAGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL8035066 | 0.79 | EDNRA (0.61) | EDNRAAGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL3839302 | 0.79 | EDNRA (0.56) | EDNRAAGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL7496869 | 0.79 | EDNRA (0.66) | EDNRAAGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL8046639 | 0.78 | EDNRA (0.65) | EDNRAAGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL795817 | 0.78 | EDNRA (1.00) | EDNRAAGTR1AGTR2KDM4EALDH1A1 | |
| SCHEMBL7496900 | 0.77 | EDNRA (0.64) | EDNRAAGTR1AGTR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143774-A | DRUGS AS HYPOTENSIVE AGENTS | HOECHST MARION ROUSSEL (FR) | 2000-11-07 | — | — | US | disclosed |