SCHEMBL8034847

SCHEMBL8034847

Cn1nc(N)c(N)c1CO

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TKT P29401 2/20 0.32
ADCY10 Q96PN6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5415677 0.83 TKT (0.42) TKT
SCHEMBL8041067 0.79 GAA (0.38)
SCHEMBL33726 0.67
SCHEMBL8025225 0.66 CDK1 (0.38)
SCHEMBL971496 0.65 KDM4E (0.34)
SCHEMBL7069490 0.64 CYP1A2 (0.39) TKT
Hydrochloric Acid SCHEMBL8139723 0.64 GAA (0.35)
SCHEMBL5405673 0.62 MPO (0.35)
SCHEMBL2725034 0.62 KDM4E (0.37)
SCHEMBL14938067 0.62 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6090162-A THE META-AMINOPHENOL IS HALOGENATED AT THE ORTHO POSITION OF THE PHENOL AS A COUPLER; DYEING USING THIS COMPOSITION WITH AN OXIDIZING AGENT; MULTICOMPARTMENT DYE KIT; USE AS HAIR DYE RESISTANT TO LIGHT, SHAMPOO, PERM TREATMENTS L'OREAL S.A. (FR) 2000-07-18 US claimed
EP-0919221-A1 Oxidative dyeing composition for keratinic fibres containing a substituted 3,4 diaminopyrazole-5 and a halogenated meta-aminophenol and dyeing process L'OREAL (FR) 1999-06-02 EP claimed
EP-0900206-A1 NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS L'OREAL (FR) 1999-03-10 EP claimed
WO-1997042173-A1 NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS L'OREAL (FR) 1997-11-13 WO claimed
CN-117479914-A Composition for lightening keratin fibers and method for lightening keratin fibers using the same 莱雅公司 2024-01-30 CN disclosed
CN-117479916-A Composition comprising at least one alkyl (poly) glycoside, at least one fatty alcohol, at least one fatty acid and at least one alkaline agent 欧莱雅 2024-01-30 CN disclosed
CN-117355287-A Composition for simultaneously bleaching and dyeing keratin fibers and method for using same 莱雅公司 2024-01-05 CN disclosed
CN-117337165-A Method for lightening keratin fibres 莱雅公司 2024-01-02 CN disclosed
CN-116634997-A Composition comprising a specific oxidation dye precursor and a specific carboxylic acid 莱雅公司 2023-08-22 CN disclosed
CN-116600779-A Process for dyeing keratin fibres with a composition comprising a particular oxidation dye precursor, a particular carboxylic acid and a chemical oxidizing agent 莱雅公司 2023-08-15 CN disclosed
CN-116568275-A Cosmetic composition comprising a combination of two specific couplers and at least one oxidation base 欧莱雅 2023-08-08 CN disclosed
CN-116546963-A Cosmetic composition comprising a combination of two specific couplers and N, N-dicarboxymethyl glutamic acid and/or salts thereof 欧莱雅 2023-08-04 CN disclosed
CN-116390710-A Use of specific amino acids as pretreatment for a method for dyeing or bleaching keratin fibers 莱雅公司 2023-07-04 CN disclosed
CN-115996699-A Pretreatment composition for a process for dyeing or bleaching keratin fibers 莱雅公司 2023-04-21 CN disclosed
CN-115996698-A Method for dyeing or bleaching keratin fibres using high concentrations of specific amino acids 莱雅公司 2023-04-21 CN disclosed
US-6118008-A FIBER-REACTIVE DYE; HAIR DYE L'OREAL (FR) 2000-09-12 US disclosed
US-6090162-A THE META-AMINOPHENOL IS HALOGENATED AT THE ORTHO POSITION OF THE PHENOL AS A COUPLER; DYEING USING THIS COMPOSITION WITH AN OXIDIZING AGENT; MULTICOMPARTMENT DYE KIT; USE AS HAIR DYE RESISTANT TO LIGHT, SHAMPOO, PERM TREATMENTS L'OREAL S.A. (FR) 2000-07-18 US disclosed
EP-0919221-A1 Oxidative dyeing composition for keratinic fibres containing a substituted 3,4 diaminopyrazole-5 and a halogenated meta-aminophenol and dyeing process L'OREAL (FR) 1999-06-02 EP disclosed
EP-0900206-A1 NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS L'OREAL (FR) 1999-03-10 EP disclosed
WO-1997042173-A1 NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS L'OREAL (FR) 1997-11-13 WO disclosed