Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029043 | 0.98 | MEN1 (0.50) | MEN1KMT2ABCHEKDM4ECHRM2 | |
| SCHEMBL7986744 | 0.97 | MEN1 (0.45) | MEN1KMT2ABCHEKDM4ECHRM2 | |
| SCHEMBL8030791 | 0.97 | MEN1 (0.45) | MEN1KMT2ABCHEKDM4ECHRM2 | |
| SCHEMBL8034855 | 0.97 | MEN1 (0.45) | MEN1KMT2ABCHEKDM4ECHRM2 | |
| SCHEMBL8032634 | 0.95 | MEN1 (0.46) | MEN1KMT2ABCHEKDM4ECHRM2 | |
| SCHEMBL8029013 | 0.94 | ALDH1A1 (0.47) | MEN1KMT2ABCHEKDM4ECHRM2 | |
| SCHEMBL7986638 | 0.94 | ALDH1A1 (0.47) | MEN1KMT2ABCHEKDM4ECHRM2 | |
| SCHEMBL8030659 | 0.94 | ALDH1A1 (0.47) | MEN1KMT2ABCHEKDM4ECHRM2 | |
| Hydrochloric Acid SCHEMBL8029202 | 0.92 | ALDH1A1 (0.46) | MEN1KMT2ABCHEKDM4ECHRM2 | |
| SCHEMBL8029031 | 0.90 | MEN1 (0.45) | MEN1KMT2ABCHEKDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |