Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12882119 | 0.84 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2PKMGAACYP1A2 | |
| SCHEMBL8029037 | 0.81 | GAA (0.62) | ALDH1A1SMN1; SMN2GAAHDAC3HDAC1 | |
| SCHEMBL24653230 | 0.80 | SMN1; SMN2 (0.75) | ALDH1A1SMN1; SMN2PKMHDAC3HDAC1 | |
| SCHEMBL1232799 | 0.80 | SMN1; SMN2 (0.75) | ALDH1A1SMN1; SMN2PKMHDAC3HDAC1 | |
| SCHEMBL8030811 | 0.80 | GAA (0.61) | ALDH1A1GAAHDAC3HDAC1CYP3A4 | |
| SCHEMBL1233157 | 0.79 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2PKMHDAC3HDAC1 | |
| SCHEMBL16266236 | 0.78 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2PKMHDAC3HDAC1 | |
| SCHEMBL9784444 | 0.77 | SMN1; SMN2 (0.84) | ALDH1A1SMN1; SMN2PKMGAAHDAC3 | |
| SCHEMBL2719119 | 0.77 | SMN1; SMN2 (0.84) | ALDH1A1SMN1; SMN2PKMGAAHDAC3 | |
| SCHEMBL15999997 | 0.77 | SMN1; SMN2 (0.84) | ALDH1A1SMN1; SMN2PKMGAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |
| CN-1046535-C | Erythromycin A 9-0-oxime derivatives endowed with antibiotic activity | ZAMBON SPA (IT) | 1999-11-17 | — | — | CN | disclosed |
| US-5847092-A | Erythromycin A 9-0 oxime derivatives endowed with antibiotic activity | ZAMBON GROUP S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |
| CN-1169727-A | Erythromycin A 9-0-oxime derivatives endowed with antibiotic activity | ZAMBON SPA (IT) | 1998-01-07 | — | — | CN | disclosed |
| EP-0797579-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018633-A1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1996-06-20 | — | — | WO | disclosed |