SCHEMBL8034883

SCHEMBL8034883

Oc1cccc2c1SC=NC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.38
BAD Q92934 1/20 0.38
ALDH1A1 P00352 2/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
HPN P05981 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX5 P09917 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
TSHR P16473 1/20 0.33
PTGS1 P23219 1/20 0.33
PDE4A P27815 1/20 0.33
KDR P35968 1/20 0.33
KMT2A Q03164 1/20 0.33
SIRT5 Q9NXA8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8583239 0.67 BCL2L1 (0.44) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL17058346 0.64
SCHEMBL27596772 0.64 BCL2L1 (0.36) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL11388095 0.61 BCL2L1 (0.34) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL10816016 0.61 BCL2L1 (0.42) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL28307322 0.59 BCL2L1 (0.39) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL7526110 0.59 BCL2L1 (0.48) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL28427093 0.58 BCL2L1 (0.48) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL6229444 0.58 BCL2L1 (0.48) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL150894 0.56 BCL2L1 (1.00) BCL2L1BADALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661039-B1 Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines BRISTOL MYERS SQUIBB CO (US) 2000-04-05 EP disclosed
EP-0661039-A1 Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines Bristol-Myers Squibb Company (US) 1995-07-05 EP disclosed
US-5374288-A Oxidative hair dyeing method, composition, and kit utilizing hydroxyl substituted benzothiazines CLAIROL INCORPORATED (US) 1994-12-20 US disclosed