SCHEMBL8583239

SCHEMBL8583239

Oc1cccc2c1SC=CC2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.44
BAD Q92934 1/20 0.44
ALDH1A1 P00352 2/20 0.34
ALOX15 P16050 2/20 0.34
HSD17B10 Q99714 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
HPN P05981 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX5 P09917 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
TSHR P16473 1/20 0.34
PTGS1 P23219 1/20 0.34
PDE4A P27815 1/20 0.34
KDR P35968 1/20 0.34
KMT2A Q03164 1/20 0.34
SIRT5 Q9NXA8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13447999 0.78 MEN1 (0.37) ALDH1A1MEN1TSHRKMT2ACA1
SCHEMBL3079817 0.76
SCHEMBL10664346 0.76 ALDH1A1 (0.34) ALDH1A1HSD17B10TDP1MEN1CYP3A4
SCHEMBL8034880 0.67 BCL2L1 (0.34) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL8034883 0.67 BCL2L1 (0.38) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL506663 0.66 BCL2L1 (0.50) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL44494 0.66 RYR2 (0.32) ALDH1A1TSHRHPGD
SCHEMBL17058346 0.66
SCHEMBL11674944 0.66 HPGD (0.38) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL7450666 0.65 BCL2L1 (0.36) BCL2L1BADALDH1A1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5496491-A FOR PHOTORESISTS, AMINE SALT REACTION PRODUCT ASHLAND OIL COMPANY (US) 1996-03-05 US claimed
US-5753601-A STABILIZING THE SOLVENT CLEANING INCLUDING A CORROSION INHIBITOR PYROGALLOL ASHLAND INC (US) 1998-05-19 US disclosed
US-5707947-A AQUEOUS PHOTORESISTS STRIPPING COMPOSITION WITH SOLVENT AND AMINE ASHLAND INC. (US) 1998-01-13 US disclosed
US-5556482-A POLAR SOLVENT AND BASIC AMINE FOR SUBSTRATES WITH PHOTORESISTS AND PHENOL COMPOUNDS ASHLAND, INC. (US) 1996-09-17 US disclosed
US-5496491-A FOR PHOTORESISTS, AMINE SALT REACTION PRODUCT ASHLAND OIL COMPANY (US) 1996-03-05 US disclosed
US-5417877-A Organic stripping composition ASHLAND INC. (US) 1995-05-23 US disclosed