Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.55 |
| ▸ | NQO2 | P16083 | 7/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575999 | 0.93 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8576002 | 0.93 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL6077926 | 0.88 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8031058 | 0.86 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL7952490 | 0.85 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8035020 | 0.84 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8035039 | 0.83 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7956065 | 0.81 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL6077655 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL8571116 | 0.81 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745586-B1 | Aryl(alkyl) propylamides, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-08 | — | — | EP | disclosed |
| US-5731352-A | THERAPY FOR DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-03-24 | — | — | US | disclosed |
| EP-0745586-A1 | Aryl(alkyl) propylamides, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-12-04 | — | — | EP | disclosed |