Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19458774 | 0.93 | HSD17B3 (0.47) | HSD17B3ESR1ESR2MIFMEN1 | |
| SCHEMBL27206840 | 0.83 | GPR84 (0.46) | ESR1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8046447 | 0.80 | HSD17B3 (0.49) | HSD17B3ESR1ESR2MIFALDH1A1 | |
| SCHEMBL11075125 | 0.79 | HSD17B3 (0.41) | HSD17B3ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL8045582 | 0.78 | ESR1 (0.54) | HSD17B3ESR1ESR2MIFCNR2 | |
| SCHEMBL8034819 | 0.74 | ESR1 (0.55) | HSD17B3ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL8043717 | 0.74 | ESR1 (0.55) | HSD17B3ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL29130050 | 0.73 | ESR1 (0.44) | HSD17B3ESR1ESR2MIFALDH1A1 | |
| SCHEMBL4951952 | 0.73 | HSD17B3 (0.48) | HSD17B3ESR1MIFMEN1ALDH1A1 | |
| SCHEMBL16769060 | 0.73 | ESR1 (0.58) | HSD17B3ESR1ESR2ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048387-A | SPECIFIED DIAZARHODAMINE LACTONE DERIVATIVE AS AN ELECTRON-DONATING COLOR-DEVELOPING ORGANIC COMPOUND | THE PILOT INK CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |