Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049473 | 0.91 | HTR1A (0.68) | HTR1AHTR1D | |
| SCHEMBL8045482 | 0.89 | HTR1A (0.70) | HTR1AHTR1D | |
| SCHEMBL8048742 | 0.89 | HTR1A (0.70) | HTR1AHTR1D | |
| SCHEMBL8046968 | 0.83 | HTR1A (0.67) | HTR1AHTR1D | |
| SCHEMBL6049939 | 0.81 | HTR1A (0.64) | HTR1AHTR1D | |
| Alniditan SCHEMBL717888 | 0.81 | HTR1A (1.00) | HTR1AHTR1D | |
| Alniditan SCHEMBL29412188 | 0.81 | HTR1A (1.00) | HTR1AHTR1D | |
| Alniditan SCHEMBL717887 | 0.81 | HTR1A (1.00) | HTR1AHTR1D | |
| Alniditan SCHEMBL7918202 | 0.80 | HTR1A (0.98) | HTR1AHTR1D | |
| Alniditan SCHEMBL7918206 | 0.80 | HTR1A (0.98) | HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100268-A | MIGRAINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2000-08-08 | — | — | US | disclosed |
| EP-0714396-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005383-A1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-02-23 | — | — | WO | disclosed |