Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127566 | 0.89 | KDM4E (0.32) | KDM4EMAPTPTGDR2 | |
| SCHEMBL7464789 | 0.88 | KDM4E (0.36) | KDM4EMAPTPTGDR2 | |
| SCHEMBL6627643 | 0.88 | KDM4E (0.34) | KDM4EMAPTPTGDR2 | |
| Hydrochloric Acid SCHEMBL7467807 | 0.85 | FLT3 (0.38) | KDM4EMAPTPTGDR2 | |
| Hydrochloric Acid SCHEMBL7469085 | 0.85 | KDM4E (0.36) | KDM4EMAPTPTGDR2 | |
| SCHEMBL6627433 | 0.84 | MAPT (0.38) | KDM4EMAPTPTGDR2 | |
| SCHEMBL6629180 | 0.84 | KDM4E (0.34) | KDM4EMAPTPTGDR2 | |
| SCHEMBL8029324 | 0.84 | KDM4E (0.34) | KDM4EMAPTPTGDR2 | |
| SCHEMBL6631577 | 0.84 | KDM4E (0.34) | KDM4EMAPTPTGDR2 | |
| SCHEMBL6628904 | 0.84 | KDM4E (0.34) | KDM4EMAPTPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080859-A | 1-CHLOROMETHYL, 3-((HETEROARYL OR ARYL)CARBONYL), 5-(HETEROCYCLE-AMINOCARBONYLOXY),7-TRIFLUOROMETHYL, 8-ALKOXYCARBONYL-1,2,3,6-TETRAHYDROPYRROLO(3,2-E)INDOLE OF GIVEN STRUCTURE; ANTITUMOR AND ANTIMICROBIAL ACTIVITY | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |