Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12508320 | 0.87 | AKR1C3 (0.58) | ENPP2AKR1C3AKR1C2ATMLMNA | |
| SCHEMBL27621305 | 0.85 | ESR1 (0.62) | ENPP2CYP1A2SCDCDK5CDK5R1 | |
| SCHEMBL29768635 | 0.85 | ESR1 (0.62) | ENPP2CYP1A2SCDCDK5CDK5R1 | |
| Bromide SCHEMBL30069821 | 0.83 | ESR1 (0.60) | ENPP2CYP1A2SCDCDK5CDK5R1 | |
| Hydrochloric Acid SCHEMBL30712192 | 0.83 | ESR1 (0.60) | ENPP2CYP1A2SCDCDK5CDK5R1 | |
| SCHEMBL27581593 | 0.83 | MEN1 (0.51) | ENPP2MEN1KMT2ACYP1A2NPC1 | |
| SCHEMBL29429154 | 0.81 | LMNA (0.60) | MEN1KMT2ACYP1A2NPC1RAB9A | |
| SCHEMBL565054 | 0.81 | LMNA (0.60) | MEN1KMT2ACYP1A2NPC1RAB9A | |
| SCHEMBL1893729 | 0.81 | LMNA (0.60) | MEN1KMT2ACYP1A2NPC1RAB9A | |
| SCHEMBL13203351 | 0.80 | AKR1C3 (0.52) | ENPP2AKR1C3AKR1C2ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150397-A | 5-(PYRIDYL, FURYL, OR THIENYL SUBSTITUTED)-6-SUBSTITUTED-2--2-NAPHTHALENESULFONAMIDES OF GIVEN FORMULA; INHIBITORS OF PROSTAGLANDIN G/H SYNTHASE; TREATING INFLAMMATORY DISEASE SUCH AS GOUT, ARTHRITIS, MYOSITIS, SYNOVITIS | SYNTEX (U.S.A.) INC. (US) | 2000-11-21 | — | — | US | disclosed |
| US-4125368-A | Metallized monoazo dyes | TOMS RIVER CHEMICAL CORP. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4058515-A | Metallized phenyl-azo-naphthol compounds | TOMS RIVER CHEMICAL CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |