Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5055339 | 0.84 | ALDH1A1 (0.58) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL28889063 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2UGT2B7 | |
| SCHEMBL5054937 | 0.84 | ALDH1A1 (0.60) | GAACYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL8035078 | 0.79 | GAA (0.64) | GAACYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL17833427 | 0.78 | ALDH1A1 (0.61) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL952648 | 0.77 | CASR (0.48) | GAAALDH1A1PBRM1L3MBTL1NPC1 | |
| SCHEMBL28391516 | 0.76 | ESR2 (0.53) | GAAALDH1A1LMNAHTTKMT2A | |
| SCHEMBL6753377 | 0.75 | UGT2B7 (0.47) | GAACYP1A2CYP2A6UGT2B7MEN1 | |
| SCHEMBL29031385 | 0.74 | ALDH1A1 (0.55) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| Acetonitrile SCHEMBL27909530 | 0.73 | CYP1A2 (0.79) | CYP1A2CYP2A6ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |