Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036315 | 0.92 | MEN1 (0.57) | PPARGMAPTMAPK1MEN1PKM | |
| SCHEMBL4540776 | 0.90 | MAPT (0.63) | MAPTMAPK1MEN1PKMKMT2A | |
| SCHEMBL8039661 | 0.88 | MAPT (0.50) | PPARGMAPTMAPK1MEN1PKM | |
| SCHEMBL4534800 | 0.87 | KMT2A (0.67) | MAPTMAPK1MEN1PKMKMT2A | |
| SCHEMBL8034144 | 0.87 | MAPT (0.66) | PPARGMAPTMAPK1MEN1PKM | |
| SCHEMBL4536613 | 0.86 | MAPT (0.55) | MAPTMAPK1MEN1PKMKMT2A | |
| SCHEMBL8041848 | 0.85 | MAPT (0.56) | PPARGMAPTMAPK1MEN1PKM | |
| SCHEMBL8034539 | 0.85 | PPARG (0.56) | PPARG | |
| SCHEMBL8024491 | 0.85 | PPARG (0.56) | PPARGMAPTMAPK1MEN1PKM | |
| SCHEMBL4542097 | 0.83 | PPARG (0.56) | PPARGMAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |