SCHEMBL8035508

SCHEMBL8035508

Cc1nc2cc(C(=O)N[C@@H](C)c3ccccc3)ccc2n1Cc1ccc(Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 1.00
RORC P51449 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8037681 1.00 PPARG (1.00) PPARGRORC
SCHEMBL8035404 0.89 PPARG (0.81) PPARG
SCHEMBL8035491 0.89 PPARG (1.00) PPARG
SCHEMBL8045639 0.89 PPARG (1.00) PPARG
SCHEMBL4564570 0.89 PPARG (1.00) PPARG
SCHEMBL16731519 0.84 PPARG (0.72) PPARG
SCHEMBL8037669 0.83 PPARG (0.85) PPARG
SCHEMBL4535196 0.82 PPARG (0.72) PPARGRORC
SCHEMBL8039981 0.82 PPARG (0.83) PPARG
SCHEMBL8024565 0.82 PPARG (0.87) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009083526-A1 NOVEL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2009-07-09 WO disclosed