Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.72 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.53 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | RHEB | Q15382 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172847 | 0.91 | PPARG (0.60) | PPARGPIK3C2BDCTPP1CCR2RHEB | |
| SCHEMBL8035707 | 0.89 | PPARG (0.64) | PPARGHTTKMT2ARORC | |
| SCHEMBL4532827 | 0.87 | PPARG (0.68) | PPARGDCTPP1TBXA2RMEN1MAPT | |
| SCHEMBL8040521 | 0.86 | PPARG (0.68) | PPARGCCR2TBXA2RAGTR1AGTR2 | |
| SCHEMBL2161614 | 0.85 | PPARG (0.65) | PPARGAGTR1AGTR2MAPTHTT | |
| SCHEMBL8028794 | 0.85 | PPARG (0.69) | PPARGCCR2TBXA2RAGTR1AGTR2 | |
| SCHEMBL8039631 | 0.85 | PPARG (0.68) | PPARGCCR2RORC | |
| SCHEMBL8028791 | 0.84 | PPARG (0.69) | PPARGCCR2RHEBTBXA2RAGTR1 | |
| SCHEMBL8039286 | 0.83 | PPARG (0.67) | PPARGCCR2RHEBTBXA2R | |
| SCHEMBL8037682 | 0.82 | PPARG (0.72) | PPARGRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |