Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 3/20 | 0.56 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.56 |
| ▸ | CKS1B | P61024 | 8/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 8/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.52 |
| ▸ | COMT | P21964 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622684 | 0.86 | PSMD14 (0.56) | PSMD14COPS5CKS1BSKP2GLO1 | |
| SCHEMBL10300323 | 0.85 | CKS1B (0.58) | CKS1BSKP2GLO1COMTTOP1 | |
| SCHEMBL12530867 | 0.79 | COMT (0.73) | CKS1BSKP2GLO1COMTKDM4E | |
| SCHEMBL28317569 | 0.79 | MEN1 (0.54) | CKS1BSKP2GLO1COMTTOP1 | |
| SCHEMBL27813415 | 0.79 | CKS1B (0.52) | CKS1BSKP2GLO1COMTTOP1 | |
| SCHEMBL28964044 | 0.77 | CKS1B (0.55) | CKS1BSKP2GLO1COMTTOP1 | |
| SCHEMBL4392334 | 0.77 | COMT (0.71) | CKS1BSKP2GLO1COMTKDM4E | |
| SCHEMBL27740416 | 0.77 | COMT (0.71) | CKS1BSKP2GLO1COMTKDM4E | |
| SCHEMBL24172386 | 0.76 | PARP1 (0.39) | KDM4E | |
| SCHEMBL18931200 | 0.76 | COMT (0.56) | PSMD14COPS5CKS1BSKP2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069151-A | Quinolines and their therapeutic use | DARWIN DISCOVERY, LTD. (GB) | 2000-05-30 | — | — | US | claimed |