Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025578 | 0.92 | TRPV1 (0.36) | CA1CA2 | |
| SCHEMBL8041385 | 0.84 | — | — | |
| SCHEMBL8025584 | 0.81 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL8039069 | 0.80 | COMT (0.40) | HSP90AA1TDP1KMT2AMEN1COMT | |
| SCHEMBL8037400 | 0.80 | TRPV1 (0.40) | KMT2AMEN1 | |
| SCHEMBL8041625 | 0.77 | EGFR (0.35) | POLBTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL8037420 | 0.74 | KMT2A (0.39) | L3MBTL1KMT2AMEN1COMT | |
| SCHEMBL8035622 | 0.73 | COMT (0.37) | POLBKMT2AMEN1COMT | |
| SCHEMBL8037287 | 0.73 | COMT (0.39) | TDP1L3MBTL1KMT2AMEN1COMT | |
| SCHEMBL8033785 | 0.73 | MEN1 (0.39) | POLBKMT2AMEN1COMTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |