Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 6/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036143 | 0.89 | MAPKAPK2 (0.48) | KDRBAZ2BMAPKAPK2CFTRCHRNB2 | |
| SCHEMBL7498322 | 0.84 | BAZ2B (0.56) | KDRBAZ2BMAPKAPK2CHRNB2CHRNB4 | |
| SCHEMBL6278936 | 0.80 | DRD2 (0.46) | KDRBAZ2BOPRM1OGFRL1MAPKAPK2 | |
| SCHEMBL6496428 | 0.80 | CFTR (0.47) | KDRBAZ2BOPRM1OGFRL1MAPKAPK2 | |
| SCHEMBL6280446 | 0.80 | CFTR (0.47) | BAZ2BOPRM1OGFRL1CFTRCHRNB2 | |
| SCHEMBL6283290 | 0.79 | CFTR (0.52) | BAZ2BOPRM1OGFRL1MAPKAPK2CFTR | |
| SCHEMBL6280948 | 0.79 | CFTR (0.43) | KDRBAZ2BOPRM1OGFRL1MAPKAPK2 | |
| SCHEMBL6278024 | 0.79 | CFTR (0.44) | KDRBAZ2BOPRM1OGFRL1CFTR | |
| SCHEMBL6280942 | 0.78 | CFTR (0.43) | KDRBAZ2BOPRM1OGFRL1CFTR | |
| SCHEMBL6282975 | 0.77 | CFTR (0.45) | OPRM1OGFRL1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048868-A | CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS; ANTIDEPRESSANTS | CEMAF (FR) | 2000-04-11 | — | — | US | disclosed |