Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025618 | 0.97 | COMT (0.40) | EPHX1COMTTBXA2RHDAC1MGLL | |
| SCHEMBL8037524 | 0.92 | POLB (0.39) | COMTHDAC1 | |
| SCHEMBL8038459 | 0.84 | TRPV1 (0.39) | TBXA2RMGLL | |
| SCHEMBL8035781 | 0.83 | EPHX2 (0.41) | EPHX1EPHX2HDAC1NAAAMGLL | |
| SCHEMBL8041445 | 0.83 | EPHX2 (0.41) | EPHX1EPHX2HDAC1NAAAMGLL | |
| SCHEMBL8035106 | 0.80 | COMT (0.36) | COMT | |
| SCHEMBL8022533 | 0.79 | G6PD (0.38) | — | |
| SCHEMBL8035190 | 0.79 | POLB (0.39) | EPHX1COMTEPHX2 | |
| SCHEMBL8035770 | 0.78 | COMT (0.38) | COMT | |
| SCHEMBL8025621 | 0.78 | POLB (0.42) | COMTTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |