Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775603 | 0.91 | HTT (0.46) | HTTL3MBTL1ALDH1A1HPGDACP3 | |
| SCHEMBL7780989 | 0.82 | HTT (0.40) | HTTL3MBTL1CYP1A2ALDH1A1HPGD | |
| SCHEMBL5692296 | 0.81 | HTT (0.41) | HTTL3MBTL1TSHRCYP1A2CYP2A6 | |
| SCHEMBL8679316 | 0.81 | CYP3A4 (0.42) | HTTL3MBTL1ALDH1A1HPGDACP3 | |
| SCHEMBL8029705 | 0.80 | TSHR (0.39) | TSHRCYP1A2CYP2A6ALDH1A1ACP3 | |
| SCHEMBL7777320 | 0.79 | CES1 (0.42) | HTTL3MBTL1CYP1A2ALDH1A1HPGD | |
| SCHEMBL7771179 | 0.79 | CYP2A6 (0.39) | TSHRCYP1A2CYP2A6ALDH1A1HPGD | |
| SCHEMBL20462902 | 0.79 | HTT (0.50) | HTTL3MBTL1CYP1A2ALDH1A1HPGD | |
| SCHEMBL25060534 | 0.78 | TSHR (0.48) | TSHRCYP1A2CYP2A6ALDH1A1WDR5 | |
| SCHEMBL8029701 | 0.77 | TSHR (0.36) | TSHRCYP1A2CYP2A6ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695756-B1 | Process for the preparation of compounds of the phosphane series as well as their use | CELANESE CHEM EUROPE GMBH (DE) | 2000-03-15 | — | — | EP | disclosed |
| US-5728886-A | Compounds of the phosphine group, their preparation and their use | HOECHST AG (DE) | 1998-03-17 | — | — | US | disclosed |
| EP-0695756-A1 | Compounds of the phosphane series, process for their preparation as well as their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | disclosed |