SCHEMBL7775603

SCHEMBL7775603

O=P(Cc1ccc2ccccc2c1-c1c(CP(=O)(c2ccccc2)c2ccccc2)ccc2ccccc12)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 6/20 0.43
HPGD P15428 1/20 0.43
ACP3 P15309 1/20 0.42
WDR5 P61964 1/20 0.41
GAA P10253 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAPT P10636 1/20 0.40
ALPG P10696 1/20 0.40
ALOX12 P18054 1/20 0.40
NPY1R P25929 1/20 0.40
NPY2R P49146 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
USP2 O75604 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8035798 0.91 HTT (0.43) HTTL3MBTL1ALDH1A1HPGDACP3
SCHEMBL8679316 0.89 CYP3A4 (0.42) HTTL3MBTL1ALDH1A1HPGDACP3
SCHEMBL7780989 0.87 HTT (0.40) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL7777320 0.87 CES1 (0.42) HTTL3MBTL1ALDH1A1HPGDACP3
SCHEMBL8023388 0.84 CYP3A4 (0.41) HTTL3MBTL1ALDH1A1HPGDACP3
SCHEMBL7777329 0.84 ACP3 (0.39) HTTL3MBTL1ALDH1A1HPGDACP3
SCHEMBL8020866 0.83 ALDH1A1 (0.46) HTTL3MBTL1ALDH1A1ACP3WDR5
SCHEMBL5692296 0.83 HTT (0.41) HTTL3MBTL1ALDH1A1HPGDACP3
SCHEMBL6544950 0.83 ACP3 (0.37) HTTL3MBTL1ALDH1A1HPGDACP3
SCHEMBL5692996 0.82 ACP3 (0.36) HTTL3MBTL1ALDH1A1HPGDACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7252280-A None JP disclosed
JP-8041086-A None JP disclosed
JP-8041086-A None JP disclosed
EP-0673944-B1 Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances CELANESE CHEM EUROPE GMBH (DE) 2001-08-16 EP disclosed
EP-0673944-B1 Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances CELANESE CHEM EUROPE GMBH (DE) 2001-08-16 EP disclosed
EP-0653432-B1 Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances CELANESE CHEM EUROPE GMBH (DE) 2000-02-09 EP disclosed
EP-0675095-B1 Process for preparing 2,2'-bis(halogenomethyl)-1,1'-binaphthalene HOECHST AG (DE) 1999-03-24 EP disclosed
EP-0571819-B1 Sulfonated 2,2'-bis(diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinic unsaturated compounds CELANESE GMBH (DE) 1998-11-11 EP disclosed
US-5767317-A Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed
US-5767317-A Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed
JP-H0841086-A PROCESS FOR PREPARING 2,2'-BIS(DIPHENYLPHOSPHINYL-METHYL)-1,1'-BINAPHTHYLS AND NOVEL COMPOUNDS FROM THIS CLASS OF SUBSTANCES HOECHST AG 1996-02-13 JP disclosed
JP-H0841086-A PROCESS FOR PREPARING 2,2'-BIS(DIPHENYLPHOSPHINYL-METHYL)-1,1'-BINAPHTHYLS AND NOVEL COMPOUNDS FROM THIS CLASS OF SUBSTANCES HOECHST AG 1996-02-13 JP disclosed
US-5481045-A Sulfonated 2,2'-bis (diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinically unsaturated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-02 US disclosed
EP-0675095-A1 Process for preparing 2,2'-bis(halogenomethyl)-1,1'-binaphthalene HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
JP-H07252280-A BIS(DIARYLALKYL)PHOSPHINES AND THEIR PREPARATION HOECHST AG 1995-10-03 JP disclosed
EP-0673944-A1 Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-27 EP disclosed
EP-0673944-A1 Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-27 EP disclosed
EP-0653432-A1 Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-17 EP disclosed
US-5347045-A Sulfonated 2,2'-bis (diphenylphosphinomethyl)-1,1'-binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinically unsaturated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-13 US disclosed
EP-0571819-A1 Sulfonated 2,2'-bis(diphenylphosphinomethyl)-1,1'binaphthalenes, process for their preparation and their use in a process for the hydroformylation of olefinic unsaturated compounds HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-01 EP disclosed