Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HCN1 | O60741 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035884 | 0.91 | HPGD (0.44) | CA14DRD3MEN1KMT2ANPC1 | |
| SCHEMBL8053214 | 0.90 | CA14 (0.39) | CA14DRD3HDAC3HDAC1LMNA | |
| SCHEMBL8047679 | 0.89 | NAMPT (0.47) | NAMPTDRD3MEN1KMT2AHDAC3 | |
| SCHEMBL8787183 | 0.88 | DRD3 (0.41) | CA14DRD3ALDH1A1HRH1HPGD | |
| SCHEMBL8045372 | 0.88 | ACKR3 (0.43) | NAMPTCA14DRD3NPC1HDAC3 | |
| SCHEMBL8035914 | 0.87 | HDAC1 (0.41) | NAMPTCA14DRD3NPC1HDAC3 | |
| SCHEMBL8035950 | 0.87 | HCRTR1 (0.38) | NAMPTCA14DRD3HDAC3HDAC1 | |
| SCHEMBL8035904 | 0.85 | NAMPT (0.46) | NAMPTCA14DRD3LMNAHPGD | |
| SCHEMBL8045204 | 0.85 | NAMPT (0.46) | NAMPTCA14DRD3HDAC3HDAC1 | |
| SCHEMBL8045274 | 0.85 | HRH1 (0.40) | NAMPTCA14DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0679649-A1 | 2,3-DIHYDROBENZOFURAN DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-11-02 | — | — | EP | disclosed |