Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035914 | 0.94 | HDAC1 (0.41) | HRH1DRD2DRD3HDAC3HDAC1 | |
| SCHEMBL8045372 | 0.92 | ACKR3 (0.43) | DRD2DRD3HDAC3HDAC1HDAC2 | |
| SCHEMBL8045204 | 0.91 | NAMPT (0.46) | HRH1DRD2DRD3HDAC3HDAC1 | |
| SCHEMBL8047095 | 0.91 | NAMPT (0.47) | HRH1DRD2DRD3HDAC3HDAC1 | |
| SCHEMBL8046983 | 0.91 | NPC1 (0.40) | HRH1HDAC3HDAC1NAMPTTMEM97 | |
| SCHEMBL8788153 | 0.90 | NAAA (0.40) | HRH1L3MBTL1DRD2DRD3HDAC3 | |
| SCHEMBL8787540 | 0.89 | HDAC3 (0.46) | DRD2DRD3HDAC3HDAC1HDAC2 | |
| SCHEMBL8035884 | 0.88 | HPGD (0.44) | HRH1DRD2DRD3HDAC3HDAC1 | |
| SCHEMBL8787545 | 0.88 | HDAC3 (0.38) | HRH1DRD2DRD3LMNAHDAC3 | |
| SCHEMBL8787728 | 0.87 | HDAC3 (0.37) | HRH1DRD2DRD3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679649-B1 | 2,3-Dihydrobenzofuran Derivatives | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0679649-A1 | 2,3-DIHYDROBENZOFURAN DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-11-02 | — | — | EP | disclosed |