SCHEMBL8035941

SCHEMBL8035941

CCOC(=O)CCN(CC)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.63
ALOX5 P09917 1/20 0.48
LTA4H P09960 2/20 0.47
CYP4F2 P78329 2/20 0.46
CYP4A11 Q02928 2/20 0.46
TP53 P04637 1/20 0.46
ALDH1A1 P00352 2/20 0.46
NPY1R P25929 1/20 0.44
NPY2R P49146 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
NOX1 Q9Y5S8 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
TSHR P16473 3/20 0.43
USP2 O75604 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10525189 0.93 SMN1; SMN2 (0.67) SMN1; SMN2ALOX5LTA4HCYP4F2CYP4A11
SCHEMBL2498213 0.91 SMN1; SMN2 (0.60) SMN1; SMN2ALOX5LTA4HCYP4F2CYP4A11
SCHEMBL9831449 0.89 SMN1; SMN2 (0.61) SMN1; SMN2ALOX5LTA4HCYP4F2CYP4A11
SCHEMBL9832157 0.88 SMN1; SMN2 (0.60) SMN1; SMN2ALOX5LTA4HCYP4F2CYP4A11
SCHEMBL11718440 0.88 SMN1; SMN2 (0.60) SMN1; SMN2ALOX5LTA4HCYP4F2CYP4A11
SCHEMBL7451762 0.86 SMN1; SMN2 (0.58) SMN1; SMN2ALOX5LTA4HCYP4F2CYP4A11
SCHEMBL7038319 0.85 MEN1 (0.49) SMN1; SMN2TP53ALDH1A1MEN1KMT2A
SCHEMBL12317868 0.85 SMN1; SMN2 (0.47) SMN1; SMN2TP53ALDH1A1MEN1KMT2A
SCHEMBL11458539 0.85 SMN1; SMN2 (0.47) SMN1; SMN2LTA4HTP53ALDH1A1MEN1
SCHEMBL11506912 0.85 SMN1; SMN2 (0.50) SMN1; SMN2TP53ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10167391-B2 Azo compound, use thereof and method for preparing same BIONEER CORPORATION (KR) 2019-01-01 US disclosed
US-20170016050-A1 NOVEL AZO COMPOUND, USE THEREOF AND METHOD FOR PREPARING SAME BIONEER CORPORATION (KR) 2017-01-19 US disclosed
US-20170016050-A1 NOVEL AZO COMPOUND, USE THEREOF AND METHOD FOR PREPARING SAME BIONEER CORPORATION (KR) 2017-01-19 US disclosed
EP-0888405-B1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEROF BASF AG (DE) 2000-04-26 EP disclosed
US-6048370-A Monoazo dyes containing a fluorosulphonyl group and use thereof BASF AKTIENGESELLSCHAFT (DE) 2000-04-11 US disclosed
EP-0888405-A1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEROF BASF AKTIENGESELLSCHAFT (DE) 1999-01-07 EP disclosed
WO-1997029155-A1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEROF BASF AKTIENGESELLSCHAFT (DE) 1997-08-14 WO disclosed
EP-0235939-A2 Thermal transfer printing ZENECA LIMITED (GB) 1987-09-09 EP disclosed
US-4313872-A MONDAZO AND DISAZO DYES CASSELLA AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed
US-4289694-A Process for the industrial preparation of water insoluble azo dyestuffs containing cyano groups from the corresponding halogen compounds PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1981-09-15 US disclosed
US-4237048-A COLORFASTNESS; FOR DYEING NATURAL AND SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1980-12-02 US disclosed
US-4105655-A PHENYL-AZO-ANILINO DYESTUFF BAYER AKTIENGESELLSCHAFT (DE) 1978-08-08 US disclosed
US-4013632-A SYNTHETIC FIBERS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-03-22 US disclosed
US-3962209-A PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10167391-B2 Azo compound, use thereof and method for preparing same CRY1, CYP51A1, CYP3A4 SMN1; SMN2 4826/4885ALOX5 512/4885LTA4H 727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.