Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 4/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030159 | 0.94 | KMT2A (0.38) | TP53MEN1GAAKMT2APARP1 | |
| SCHEMBL8030164 | 0.91 | ALDH1A1 (0.37) | TP53MEN1GAAKMT2ABDKRB2 | |
| SCHEMBL8020871 | 0.90 | CNR1 (0.35) | MEN1GAAKMT2ABDKRB2HPSE | |
| SCHEMBL8030482 | 0.90 | CNR1 (0.37) | MEN1GAAKMT2ABDKRB2 | |
| SCHEMBL8030147 | 0.87 | KMT2A (0.36) | MEN1GAAKMT2ABDKRB2ITGB1 | |
| SCHEMBL8030430 | 0.87 | MEN1 (0.36) | MEN1GAAKMT2ABDKRB2HPSE | |
| SCHEMBL8020746 | 0.87 | MEN1 (0.35) | MEN1GAAKMT2ABDKRB2ITGB1 | |
| SCHEMBL8029560 | 0.86 | MEN1 (0.36) | MEN1GAAKMT2ABDKRB2 | |
| SCHEMBL8020734 | 0.86 | KMT2A (0.40) | MEN1GAAKMT2ABDKRB2ITGB1 | |
| SCHEMBL8020735 | 0.85 | MEN1 (0.36) | MEN1GAAKMT2ABDKRB2ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |