Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13685725 | 0.88 | — | — | |
| SCHEMBL8291430 | 0.88 | — | — | |
| SCHEMBL8290345 | 0.88 | — | — | |
| SCHEMBL12608386 | 0.88 | — | — | |
| SCHEMBL12855918 | 0.83 | — | — | |
| SCHEMBL13685442 | 0.83 | PPIA (0.32) | PSMB9PSMB8 | |
| SCHEMBL8289630 | 0.81 | PPIA (0.31) | PSMB9PSMB8 | |
| SCHEMBL8291490 | 0.81 | PPIA (0.31) | PSMB9PSMB8 | |
| SCHEMBL8290280 | 0.81 | BACE1 (0.31) | — | |
| SCHEMBL8050876 | 0.81 | BACE1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058856-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2009-05-07 | — | — | WO | disclosed |