Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 12/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16800540 | 0.89 | SLC6A9 (0.51) | SLC6A9SIGMAR1HSD17B10 | |
| SCHEMBL9182778 | 0.89 | SLC6A9 (0.51) | SLC6A9SIGMAR1HSD17B10 | |
| SCHEMBL1144711 | 0.89 | SLC6A9 (0.51) | SLC6A9SIGMAR1HSD17B10 | |
| SCHEMBL16660369 | 0.87 | SLC6A9 (0.53) | SLC6A9SIGMAR1HSD17B10 | |
| SCHEMBL2290670 | 0.87 | SLC6A9 (0.53) | SLC6A9SIGMAR1HSD17B10 | |
| SCHEMBL24709148 | 0.86 | SLC6A9 (0.43) | SLC6A9SIGMAR1HSD17B10 | |
| SCHEMBL16660371 | 0.83 | SLC6A9 (0.47) | SLC6A9SIGMAR1HSD17B10 | |
| SCHEMBL16660370 | 0.83 | SLC6A9 (0.47) | SLC6A9SIGMAR1HSD17B10 | |
| SCHEMBL20978841 | 0.81 | SLC6A9 (0.44) | SLC6A9SIGMAR1HSD17B10 | |
| SCHEMBL2799303 | 0.81 | SLC6A9 (0.44) | SLC6A9SIGMAR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143274-A | IMAGING MAMMALIAN TISSUE UTILIZING A NON-IONIC COMPLEX OF A PARAMAGNETIC ION OF LANTHANIDE ELEMENT AND A MACROCYCLIC CHELATING AGENT | BRACCO DIAGNOSTICS, INC. | 2000-11-07 | — | — | US | disclosed |
| US-5846519-A | Method for imaging mammalian tissue using 1-substituted-1,4,7-tricarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs | BRACCO DIAGNOSTICS INC. (US) | 1998-12-08 | — | — | US | disclosed |
| US-5674470-A | Method for imaging mammalian tissue using 1-substituted- 4,7,10-tricarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs | BRACCO DIAGNOSTICS INC. (US) | 1997-10-07 | — | — | US | disclosed |
| EP-0292689-B1 | Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs | BRACCO INT BV (NL) | 1996-07-31 | — | — | EP | disclosed |
| US-5474756-A | Chelate compound of a paramagnetic ion of lanthanide element | BRACCO INTERNATIONAL B.V. (NL) | 1995-12-12 | — | — | US | disclosed |
| US-4885363-A | RADIOPHARMACEUTICAL IMAGING; MEDICAL DIAGNOSIS | E. R. SQUIBB & SONS, INC. (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0292689-A2 | Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs | BRACCO INTERNATIONAL B.V. (NL) | 1988-11-30 | — | — | EP | disclosed |