Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249283 | 0.96 | HDAC4 (0.35) | HDAC4LMNAPOLBDGAT1CNR1 | |
| SCHEMBL9249290 | 0.96 | HDAC4 (0.35) | HDAC4LMNAPOLBDGAT1CNR1 | |
| SCHEMBL9249148 | 0.89 | HDAC4 (0.34) | HDAC4LMNAPOLBDGAT1CNR1 | |
| SCHEMBL9249143 | 0.89 | HDAC4 (0.34) | HDAC4LMNAPOLBDGAT1CNR1 | |
| SCHEMBL9139302 | 0.87 | LMNA (0.36) | LMNAPOLBCNR1MAOBSMN1; SMN2 | |
| SCHEMBL8036306 | 0.86 | ESR2 (0.38) | LMNADGAT1KDM1AMAOBSOAT1 | |
| SCHEMBL8034655 | 0.83 | HDAC4 (0.36) | HDAC4LMNAPOLBKDM1AMAOB | |
| SCHEMBL9136639 | 0.83 | ESR2 (0.40) | LMNAMAPK1IDO1 | |
| SCHEMBL8034648 | 0.82 | ESR2 (0.41) | LMNADGAT1KDM1AMAOBSOAT1 | |
| SCHEMBL8024987 | 0.81 | HDAC4 (0.32) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497176-B1 | Four rings compounds and liquid crystal mixtures containing them | MERCK PATENT GMBH (DE) | 2000-04-05 | — | — | EP | disclosed |
| US-5478497-A | For electro-optical purposes | HOFFMANN-LA ROCHE INC. (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0497176-A2 | Four rings compounds and liquid crystal mixtures containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |