Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038387 | 0.88 | KDM4E (0.46) | MAPTCYP1A2POLBSIRT2SIRT1 | |
| SCHEMBL4007802 | 0.86 | ATM (0.40) | NPSR1TP53ALDH1A1 | |
| SCHEMBL4010115 | 0.84 | MAPT (0.39) | MAPTCYP1A2POLBSIRT2SIRT1 | |
| SCHEMBL8031450 | 0.84 | CYP1A2 (0.47) | MAPTCYP1A2POLBSIRT2SIRT1 | |
| SCHEMBL8024769 | 0.84 | MAPT (0.45) | MAPTCYP1A2POLBSIRT2SIRT1 | |
| SCHEMBL8034697 | 0.84 | MAPT (0.40) | MAPTCYP1A2POLBSIRT2SIRT1 | |
| SCHEMBL8021652 | 0.84 | CYP1A2 (0.42) | MAPTCYP1A2POLBGAANPSR1 | |
| SCHEMBL8030927 | 0.83 | ATM (0.46) | MAPTCYP1A2POLBSIRT2SIRT1 | |
| SCHEMBL8034434 | 0.81 | LMNA (0.44) | MAPTCYP1A2POLBSIRT2SIRT1 | |
| SCHEMBL8043414 | 0.81 | TARBP2 (0.46) | MAPTPOLBSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |