Carmofur

Carmofur

SCHEMBL8037

CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ASAH1 Q13510 3/20 1.00
LMNA P02545 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
MAPK3 P27361 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
SQOR Q9Y6N5 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11601957 1.00 ASAH1 (1.00) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL11665159 1.00 ASAH1 (1.00) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL10933495 1.00 ASAH1 (1.00) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL11602950 1.00 ASAH1 (1.00) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL11603162 0.99 ASAH1 (0.97) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL10631384 0.96 ASAH1 (0.93) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL10458638 0.95 ASAH1 (0.90) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL11601229 0.89 ASAH1 (0.80) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL9775183 0.88 ASAH1 (0.79) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL10479199 0.87 ASAH1 (0.77) ASAH1LMNACYP3A4CYP2D6MAPK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 41201 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4228644-B1 N-[4-[1-(1,4-DIOXASPIRO[4.5]DEC-8-YL)-4-(8-OXA-3-AZABICYCLO[3.2.1]OCT-3-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-6-YL]PHENYL]-N'-METHYLUREA FOR USE IN THE TREATMENT OF COVID19 NANTCELL INC (US) 2026-05-27 EP claimed
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
US-20260137636-A1 TUMOR-TARGETING THIOCOLCHICINE NANOEMULSION SMITH HENRY (US) 2026-05-21 US claimed
EP-4743490-A1 HUMANIZED ANTI-CD7 ANTIBODY Christian-Albrechts-Universität zu Kiel (DE) 2026-05-20 EP claimed
US-12629427-B2 Nanosystems as selective vehicles SERVIZO GALEGO DE SAÚDE FUNDACIÓN INSTITUTO DE INVESTIGACIÓN SANITARIA DE SANTIAGO DE COMPOSTELA (FIDIS) 2026-05-19 US claimed
WO-2026099502-A1 NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2026-05-15 WO claimed
CN-122028934-A Combination of CLDN18_2 antibody and chemotherapeutic drug and application thereof 江苏奥赛康生物医药有限公司 2026-05-12 CN claimed
US-20260115305-A1 LINKERS, CONJUGATES AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE SUZHOU CO LTD (CN) 2026-04-30 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
EP-4725496-A2 N-[4-[1-(1,4-DIOXASPIRO[4.5]DEC-8-YL)-4-(8-OXA-3-AZABICYCLO[3.2.1]OCT-3-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-6-YL]PHENYL]-N'-METHYLUREA FOR USE IN THE TREATMENT OF COVID19 NantCell, Inc. (US) 2026-04-15 EP claimed
EP-0180188-B1 A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP claimed
US-5024998-A Administering in aqueous solution with cyclodextrin derivative UNIVERSITY OF FLORIDA (US) 1991-06-18 US claimed
US-4983586-A Decreasing precipitation at injection site or in lungs or other organs by combining with hydroxypropyl-beta-cyclodextrin UNIVERSITY OF FLORIDA (US) 1991-01-08 US claimed
EP-0393575-A1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent G.D. Searle & Co. (US) 1990-10-24 EP claimed
EP-0335545-A2 Pharmaceutical formulations for parenteral use UNIVERSITY OF FLORIDA (US) 1989-10-04 EP claimed
US-4622325-A Anti-cancer composition for delivering 5-fluorouracil TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1986-11-11 US claimed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP claimed
US-4578391-A Oily compositions of antitumor drugs YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-03-25 US claimed
US-4481203-A ANTICANCER AGENTS TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1984-11-06 US claimed
US-4071519-A 1-Carbamoyl-5-fluorouracil derivatives MITSUI TOATSU CHEMICALS, INCORPORATED (JA) 1978-01-31 US claimed