Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.79 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11262305 | 0.99 | ASAH1 (0.77) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| Hydrochloric Acid SCHEMBL11253098 | 0.93 | LMNA (0.72) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11601957 | 0.88 | ASAH1 (1.00) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11602950 | 0.88 | ASAH1 (1.00) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL10933495 | 0.88 | ASAH1 (1.00) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11665159 | 0.88 | ASAH1 (1.00) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| Carmofur SCHEMBL8037 | 0.88 | ASAH1 (1.00) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL29001286 | 0.87 | ASAH1 (0.75) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11603162 | 0.86 | ASAH1 (0.97) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL10479235 | 0.86 | ASAH1 (0.77) | ASAH1LMNACYP3A4CYP2D6MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049551-A | Antitumor | UBE INDUSTRIES, LTD. (JP) | 1991-09-17 | — | — | US | disclosed |
| EP-0400610-A1 | 5-Fluorouracil derivatives | UBE INDUSTRIES, LTD. (JP) | 1990-12-05 | — | — | EP | disclosed |