Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylaniline SCHEMBL9275568 | 0.98 | TSHR (0.53) | TSHRCNR2TAAR1MEN1RAB9A | |
| SCHEMBL11318715 | 0.92 | TSHR (0.52) | TSHRCNR2TAAR1MEN1RAB9A | |
| Diethylaniline SCHEMBL18092109 | 0.89 | TSHR (0.57) | TSHRCNR2TAAR1MEN1RAB9A | |
| Diethylaniline SCHEMBL7924329 | 0.88 | TSHR (0.52) | TSHRCNR2TAAR1MEN1RAB9A | |
| SCHEMBL2917098 | 0.86 | TSHR (0.59) | TSHRCNR2TAAR1MEN1RAB9A | |
| Diethylaniline SCHEMBL17594 | 0.86 | TSHR (0.70) | TSHRCNR2TAAR1MEN1RAB9A | |
| Diethylaniline SCHEMBL9000098 | 0.86 | TSHR (0.70) | TSHRCNR2TAAR1MEN1RAB9A | |
| Ammonia Solution, Strong SCHEMBL11317315 | 0.84 | TSHR (0.57) | TSHRCNR2TAAR1MEN1RAB9A | |
| Diethylaniline SCHEMBL9789921 | 0.84 | TSHR (0.61) | TSHRCNR2TAAR1MEN1RAB9A | |
| SCHEMBL96435 | 0.84 | HTR1A (0.48) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644193-B1 | Process for preparing 2-acetylamino-6-chloropurine | JUZEN CHEMICAL CO LTD (JP) | 2000-04-26 | — | — | EP | disclosed |