Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021755 | 0.89 | KDM4E (0.39) | KDM4ERAB9AHSD17B10ALDH1A1TSHR | |
| SCHEMBL8038387 | 0.87 | KDM4E (0.46) | KDM4ERAB9ATP53HSD17B10LMNA | |
| SCHEMBL8036895 | 0.76 | MAPT (0.40) | RAB9ATP53LMNACACNB4CACNA1A | |
| SCHEMBL8034697 | 0.76 | MAPT (0.40) | RAB9ATP53LMNACACNB4CACNA1A | |
| SCHEMBL8040695 | 0.75 | CNR1 (0.46) | KDM4ERAB9ATP53HSD17B10LMNA | |
| SCHEMBL8030988 | 0.75 | KDM4E (0.53) | KDM4ERAB9ATP53HSD17B10LMNA | |
| SCHEMBL8031451 | 0.75 | KDM4E (0.46) | KDM4ERAB9ATP53HSD17B10LMNA | |
| SCHEMBL8037711 | 0.74 | KDM4E (0.47) | KDM4ERAB9AHSD17B10ALDH1A1TSHR | |
| SCHEMBL8036018 | 0.73 | KDM4E (0.56) | KDM4ERAB9ATP53HSD17B10LMNA | |
| SCHEMBL8021662 | 0.72 | KDM4E (0.50) | KDM4ERAB9ATP53HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |