SCHEMBL8037437

SCHEMBL8037437

C[Si](C)(C)OC1CC=CCC1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7103931 1.00
SCHEMBL3677598 0.73 ALDH1A1 (0.32)
SCHEMBL3667942 0.69 GSR (0.32)
SCHEMBL3667944 0.69 GSR (0.32)
SCHEMBL3678002 0.68
SCHEMBL3678001 0.68
SCHEMBL3669898 0.68
SCHEMBL11348891 0.68
SCHEMBL3680672 0.67
SCHEMBL7101091 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0994882-A1 MANUFACTURE OF OPTICALLY ACTIVE HALOHYDRIN TRIALKYLSILYL ETHERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2000-04-26 EP disclosed
WO-1999002535-A1 MANUFACTURE OF OPTICALLY ACTIVE HALOHYDRIN TRIALKYLSILYL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-21 WO disclosed