SCHEMBL8037491

SCHEMBL8037491

CC(C)OC(=O)c1ooc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
CA12 O43570 6/20 0.39
CA1 P00915 6/20 0.39
CA2 P00918 6/20 0.39
CA7 P43166 6/20 0.39
CA9 Q16790 6/20 0.39
CA14 Q9ULX7 6/20 0.39
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 2/20 0.37
CYP1A2 P05177 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 2/20 0.35
HTT P42858 2/20 0.35
RAB9A P51151 2/20 0.35
HCAR2 Q8TDS4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3244755 0.78 CA12 (0.36) PDCD1CD274CA12CA1CA2
SCHEMBL8043889 0.72 CA12 (0.33) PDCD1CD274CA12CA1CA2
SCHEMBL4353430 0.72 CYP1A2 (0.59) CA1CA2CA9ALDH1A1TSHR
SCHEMBL20807029 0.65 CYP4F2 (0.46) PDCD1CD274CA12CA1CA2
SCHEMBL28737047 0.65 CA12 (0.43) PDCD1CD274CA12CA1CA2
SCHEMBL10594992 0.65 CA12 (0.52) PDCD1CD274CA12CA1CA2
SCHEMBL10594997 0.65 CA12 (0.52) PDCD1CD274CA12CA1CA2
SCHEMBL5839605 0.65 CA12 (0.64) PDCD1CD274CA12CA1CA2
SCHEMBL15116002 0.65 CA12 (0.52) PDCD1CD274CA12CA1CA2
SCHEMBL6228537 0.65 CA1 (0.70) PDCD1CD274CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127325-A GRAFT COPOLYMER OF AN OIL-SOLUBLE OLEFIN POLYMER AND OF A COPOLYMER (B) OF A MONOMER HAVING A PEROXIDE BOND WITH (METH)ACRYLATE; OR COPOLYMER (C) OF A PEROXIDE CONTAINING MONOMER AND SPECIFIED MONOMERS; NO PHASE SEPARATION NOF CORPORATION (JP) 2000-10-03 US disclosed
EP-0872539-A1 VISCOSITY INDEX IMPROVER, PROCESS FOR PREPARING THE SAME AND LUBRICATING OIL COMPOSITION NOF CORPORATION (JP) 1998-10-21 EP disclosed