SCHEMBL8043889

SCHEMBL8043889

CCC(C)(C)OC(=O)c1ooc1C(=O)OC(C)C

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.33
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
CA7 P43166 4/20 0.33
CA9 Q16790 4/20 0.33
CA14 Q9ULX7 4/20 0.33
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3244755 0.82 CA12 (0.36) CA12CA1CA2CA7CA9
SCHEMBL29335004 0.77 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL8039509 0.77 ALDH1A1 (0.40) ALDH1A1LMNA
SCHEMBL8037479 0.74 TSHR (0.42) ALDH1A1LMNAHSD17B10
SCHEMBL8037491 0.72 PDCD1 (0.40) CA12CA1CA2CA7CA9
SCHEMBL6896990 0.72 TSHR (0.37) ALDH1A1LMNA
SCHEMBL8027511 0.72 MAPT (0.41) KDM4EALDH1A1HSD17B10
SCHEMBL28949349 0.68 LMNA (0.40) ALDH1A1LMNA
SCHEMBL8039496 0.67 CYP2C9 (0.40) CA12CA1CA2CA9CA14
SCHEMBL5366422 0.65 CYP1A2 (0.49) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127325-A GRAFT COPOLYMER OF AN OIL-SOLUBLE OLEFIN POLYMER AND OF A COPOLYMER (B) OF A MONOMER HAVING A PEROXIDE BOND WITH (METH)ACRYLATE; OR COPOLYMER (C) OF A PEROXIDE CONTAINING MONOMER AND SPECIFIED MONOMERS; NO PHASE SEPARATION NOF CORPORATION (JP) 2000-10-03 US disclosed
EP-0872539-A1 VISCOSITY INDEX IMPROVER, PROCESS FOR PREPARING THE SAME AND LUBRICATING OIL COMPOSITION NOF CORPORATION (JP) 1998-10-21 EP disclosed