Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | WNK1 | Q9H4A3 | 3/20 | 0.43 |
| ▸ | ESRRA | P11474 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903796 | 0.75 | CYP11B1 (0.56) | CYP11B1HSD11B1CYP11B2RAB9APHGDH | |
| SCHEMBL8032535 | 0.75 | IDO1 (0.47) | IDO1WNK1ESRRANPC1RAB9A | |
| SCHEMBL15635313 | 0.72 | CYP11B1 (0.57) | CYP11B1HSD11B1CYP11B2RAB9APHGDH | |
| Hydrochloric Acid SCHEMBL31169762 | 0.70 | CXCR4 (0.61) | ESRRANPC1RAB9A | |
| SCHEMBL10275021 | 0.70 | CYP11B1 (0.57) | CYP11B1HSD11B1CYP11B2NPC1RAB9A | |
| SCHEMBL2979417 | 0.70 | KMT2A (0.56) | HSD11B1ESRRANPC1RAB9A | |
| SCHEMBL27549688 | 0.69 | CYP11B1 (0.56) | CYP11B1HSD11B1CYP11B2NPC1RAB9A | |
| SCHEMBL7603669 | 0.68 | CXCR4 (0.63) | ESRRANPC1RAB9A | |
| SCHEMBL10764797 | 0.68 | CXCR4 (0.63) | ESRRANPC1RAB9A | |
| SCHEMBL8039797 | 0.68 | HIF1A (0.54) | IDO1WNK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071706-A1 | PYRAZOLEPYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2009-06-11 | — | — | WO | disclosed |