SCHEMBL8038433

SCHEMBL8038433

CCCCCCCCCCCCCCP(C)(=O)CC.CCCCCCCCCCCCP(C)(C)=O

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 10/20 0.50
LPAR3 Q9UBY5 3/20 0.48
LPAR2 Q9HBW0 1/20 0.48
FAAH O00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6189569 0.93 LPAR3 (0.54) TRPM8LPAR3LPAR2FAAH
SCHEMBL11266848 0.93 LPAR3 (0.54) TRPM8LPAR3LPAR2FAAH
SCHEMBL10933864 0.93 LPAR3 (0.54) TRPM8LPAR3LPAR2FAAH
SCHEMBL10935082 0.93 LPAR3 (0.54) TRPM8LPAR3LPAR2FAAH
SCHEMBL315167 0.93 LPAR3 (0.54) TRPM8LPAR3LPAR2FAAH
SCHEMBL408220 0.88 TRPM8 (0.61) TRPM8LPAR3LPAR2FAAH
SCHEMBL1725369 0.88 TRPM8 (0.61) TRPM8LPAR3LPAR2FAAH
SCHEMBL158223 0.88 TRPM8 (0.61) TRPM8LPAR3LPAR2FAAH
SCHEMBL314020 0.88 TRPM8 (0.61) TRPM8LPAR3LPAR2FAAH
SCHEMBL992086 0.88 TRPM8 (0.61) TRPM8LPAR3LPAR2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996413-A1 SUN PROTECTION COMPOSITION Colgate-Palmolive Company (US) 2000-05-03 EP disclosed
WO-1999013854-A1 SUN PROTECTION COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1999-03-25 WO disclosed