Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727933 | 0.85 | TDP1 (0.50) | CARM1PRMT6TDP1CHRNB2CHRNA5 | |
| SCHEMBL8447322 | 0.82 | CARM1 (0.61) | CARM1PRMT6TDP1CHRNB2CHRNA5 | |
| SCHEMBL532785 | 0.82 | CARM1 (0.61) | CARM1PRMT6TDP1CHRNB2CHRNA5 | |
| SCHEMBL22005207 | 0.79 | CARM1 (0.58) | CARM1PRMT6TDP1CHRNB2CHRNA5 | |
| SCHEMBL1026556 | 0.79 | TDP1 (0.52) | CARM1PRMT6TDP1CHRNB2CHRNA5 | |
| SCHEMBL25445958 | 0.79 | CARM1 (0.58) | CARM1PRMT6TDP1CHRNB2CHRNA5 | |
| SCHEMBL2023266 | 0.78 | ALDH1A1 (0.51) | CARM1PRMT6TDP1CHRNB2CHRNA5 | |
| SCHEMBL9118362 | 0.78 | ALDH1A1 (0.51) | CARM1PRMT6TDP1CHRNB2CHRNA5 | |
| SCHEMBL2022684 | 0.78 | ALDH1A1 (0.51) | CARM1PRMT6TDP1CHRNB2CHRNA5 | |
| SCHEMBL12959087 | 0.78 | TDP1 (0.50) | CARM1PRMT6TDP1CHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080750-A | FOR PROPHYLAXIS AND TREATMENT OF DISEASES CAUSED BY INFECTION BY ROTAVIRUS | NIPPON SHOJI KAISHA LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0806418-A2 | Novel pyrimidine compound and anti-rotavirus agent | NIPPON SHOJI KAISHA, LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |