Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4618228 | 0.85 | SLC6A2 (0.45) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3347205 | 0.80 | SLC6A4 (0.51) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8038690 | 0.80 | SLC6A4 (0.51) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL3930855 | 0.78 | SLC6A4 (0.52) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3709825 | 0.77 | NQO1 (0.40) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4627006 | 0.76 | OPRM1 (0.39) | OPRM1OPRD1HTR2ASLC6A2SLC6A4 | |
| Acetic Acid SCHEMBL5795551 | 0.74 | SLC6A4 (0.46) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12495465 | 0.74 | OPRM1 (0.36) | DPP4OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4361544 | 0.73 | LMNA (0.45) | SLC6A2SLC6A3 | |
| SCHEMBL12682199 | 0.73 | SCN4A (0.41) | DPP4OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917237-A2 | PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE | Teva Pharmaceutical Industries Ltd (IL) | 2008-05-07 | — | — | EP | claimed |
| WO-2008013994-A2 | PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-01-31 | — | — | WO | claimed |
| EP-1917237-A2 | PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE | Teva Pharmaceutical Industries Ltd (IL) | 2008-05-07 | — | — | EP | disclosed |
| WO-2008013994-A2 | PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-01-31 | — | — | WO | disclosed |