Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PAM | P19021 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624584 | 1.00 | MAPT (0.61) | MAPTLMNADGKAKDM4EDUSP3 | |
| SCHEMBL8050066 | 1.00 | MAPT (0.61) | MAPTLMNADGKAKDM4EDUSP3 | |
| SCHEMBL28398337 | 1.00 | MAPT (0.61) | MAPTLMNADGKAKDM4EDUSP3 | |
| SCHEMBL408885 | 1.00 | MAPT (0.61) | MAPTLMNADGKAKDM4EDUSP3 | |
| SCHEMBL27952812 | 0.98 | MAPT (0.59) | MAPTLMNADGKAKDM4EDUSP3 | |
| SCHEMBL29197325 | 0.98 | MAPT (0.62) | MAPTLMNADGKAKDM4EDUSP3 | |
| SCHEMBL2254700 | 0.98 | MAPT (0.62) | MAPTLMNADGKAKDM4EDUSP3 | |
| SCHEMBL2253473 | 0.98 | MAPT (0.62) | MAPTLMNADGKAKDM4EDUSP3 | |
| SCHEMBL29196948 | 0.98 | MAPT (0.62) | MAPTLMNADGKAKDM4EDUSP3 | |
| SCHEMBL2258521 | 0.98 | MAPT (0.62) | MAPTLMNADGKAKDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022916-A | MELT EXTRUSION OF PHOSPHITE STABILIZED POLYOLEFIN COMPOSITIONS SUBJECT TO SOLID BY-PRODUCT FORMATION DURING MELT EXTRUSION IS IMPROVED BY THE ADDITION OF A METAL SALT OF A LACTIC ACID TO THE COMPOSITION. | GENERAL ELECTRIC COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
| US-5414034-A | Polyolefin, bis/2,6-di-t-butyl-4-methylphenyl/ pentaerythritol diphosphite, and metal lactate; reduced screen pack plugging during melt extrusion | GENERAL ELECTRIC COMPANY (US) | 1995-05-09 | — | — | US | disclosed |
| EP-0618314-A1 | Improved processing stabilizer formulations | GENERAL ELECTRIC COMPANY (US) | 1994-10-05 | — | — | EP | disclosed |