Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1054333 | 0.81 | P2RY6 (0.44) | ABL1RIN1ADORA3P2RY6P2RY14 | |
| SCHEMBL8038969 | 0.81 | ABL1 (0.59) | ABL1RIN1ADORA3P2RY6P2RY14 | |
| SCHEMBL23056605 | 0.80 | ABL1 (0.65) | ABL1RIN1ADORA3P2RY6P2RY14 | |
| SCHEMBL8038983 | 0.80 | TYMP (0.47) | ADORA3POLBNPC1RAB9ATYMP | |
| SCHEMBL1055228 | 0.80 | P2RY6 (0.43) | ABL1RIN1ADORA3P2RY6P2RY14 | |
| SCHEMBL4338084 | 0.80 | P2RY6 (0.43) | ABL1RIN1ADORA3P2RY6P2RY14 | |
| SCHEMBL23140727 | 0.80 | ABL1 (0.51) | ABL1RIN1ADORA3P2RY6P2RY14 | |
| SCHEMBL23157266 | 0.79 | POLB (0.56) | ABL1RIN1ADORA3P2RY6P2RY14 | |
| SCHEMBL23056641 | 0.79 | POLB (0.56) | ABL1RIN1ADORA3P2RY6P2RY14 | |
| SCHEMBL5358852 | 0.79 | POLB (0.56) | ABL1RIN1ADORA3P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084082-A | SOLID PHASE SYNTHESIS BY ATTACHING BETA-LACTAM HAVING NUCLEOBASE TO SOLID SUPPORT, DEPROTECTING HYDROXY GROUP, REACTING FREE HYDROXYL GROUP WITH BETA-LACTAMTIDE HAVING ACTIVATED PHOSPHITE GROUP, AND OXIDIZING | ISIS PHARMACEUTICALS, INC. (US) | 2000-07-04 | — | — | US | disclosed |
| US-5866691-A | Lactam nucleic acids | ISIS PHARMACEUTICALS, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5554746-A | Lactam nucleic acids | ISIS PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | disclosed |