SCHEMBL8039082

SCHEMBL8039082

CCCCCCCCCCCCP(CCCC)(CCCC)(CCCC)OS(=O)(=O)c1cc(C(=O)O)cc(C(=O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.44
S1PR3 Q99500 6/20 0.41
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
PLA2G4B P0C869 1/20 0.38
S1PR1 P21453 2/20 0.37
RARB P10826 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1256590 0.96 LCK (0.42) PLA2G2AS1PR3LCKFYNTP53
SCHEMBL3902079 0.90 LCK (0.40) PLA2G2AS1PR3LCKFYNTP53
SCHEMBL11514902 0.87 LMNA (0.38)
SCHEMBL3905039 0.84 S1PR3 (0.40) S1PR3TSHRS1PR1
SCHEMBL2026570 0.83 LCK (0.41) PLA2G2AS1PR3LCKFYNTP53
SCHEMBL3914607 0.83 F2 (0.43) S1PR3PLA2G4B
SCHEMBL3686362 0.82 LMNA (0.40)
SCHEMBL4739947 0.81 POLB (0.41) PLA2G2AS1PR3TP53TSHRPLA2G4B
SCHEMBL11681887 0.81 CA12 (0.43)
SCHEMBL3914601 0.78 S1PR3 (0.41) PLA2G2AS1PR3LCKFYNTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000095789-A PRODUCTION OF PHOSPHONIUM SULFOISOPHTHALATE DERIVATIVE NIPPON CHEM IND CO LTD 2000-04-04 JP disclosed