Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 3/20 | 0.35 |
| ▸ | FNTB | P49356 | 3/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8029623 | 0.99 | HCRTR1 (0.41) | HCRTR1HCRTR2HSD11B1BACE1BACE2 | |
| Hydrochloric Acid SCHEMBL7420338 | 0.99 | HCRTR1 (0.41) | HCRTR1HCRTR2HSD11B1BACE1BACE2 | |
| SCHEMBL7424077 | 0.87 | KDM4E (0.35) | FNTAFNTBPGGT1BKDM4EALDH1A1 | |
| SCHEMBL7423151 | 0.87 | KDM4E (0.35) | FNTAFNTBPGGT1BKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8040100 | 0.86 | KDM4E (0.35) | FNTAFNTBPGGT1BKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7423721 | 0.86 | KDM4E (0.35) | FNTAFNTBPGGT1BKDM4EALDH1A1 | |
| SCHEMBL7425272 | 0.85 | KDM1A (0.36) | FNTAFNTBPGGT1BKDM1AKDM4E | |
| SCHEMBL8040958 | 0.85 | KDM1A (0.36) | FNTAFNTBPGGT1BKDM1AKDM4E | |
| Hydrochloric Acid SCHEMBL7425419 | 0.84 | ACHE (0.37) | FNTAFNTBPGGT1BKDM1AKDM4E | |
| Hydrochloric Acid SCHEMBL7423170 | 0.84 | ACHE (0.37) | FNTAFNTBPGGT1BKDM1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034093-A | Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 2000-03-07 | — | — | US | disclosed |