SCHEMBL8039253

SCHEMBL8039253

CC#CCC1CCC(c2ccc(C#Cc3ccc(OCCC)cc3)cc2)CC1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACACB O00763 12/20 0.45
RAB9A P51151 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
CYP2C9 P11712 2/20 0.37
HRH3 Q9Y5N1 2/20 0.37
CYP3A4 P08684 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8029212 0.90 ACACB (0.42) ACACBRAB9AMAOAMAOBALDH1A1
SCHEMBL8046489 0.89 ACACB (0.42) ACACBRAB9AMAOAMAOBALDH1A1
SCHEMBL8039152 0.86 APP (0.44) ACACBKCNH2
SCHEMBL9512374 0.85 ACACB (0.46) ACACBRAB9AMAOAMAOBALDH1A1
SCHEMBL5352047 0.84 ACACB (0.48) ACACBRAB9AMAOAMAOBALDH1A1
SCHEMBL9511281 0.82 ACACB (0.46) ACACBRAB9AMAOAMAOBALDH1A1
SCHEMBL9510031 0.82 ACACB (0.44) ACACBRAB9AMAOAMAOBALDH1A1
SCHEMBL8046325 0.82 SPHK1 (0.41) ACACB
SCHEMBL8040935 0.82 ACACB (0.36) ACACBALDH1A1MAPTCYP2C9CYP3A4
SCHEMBL8045708 0.81 FFAR1 (0.41) ACACBCYP2C9CYP3A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727473-B1 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-01-12 EP disclosed
US-5833879-A LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES CHISSO CORPORATION (JP) 1998-11-10 US disclosed
EP-0727473-A2 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-08-21 EP disclosed