Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046401 | 0.87 | APP (0.42) | APPDRD2GRM3CHRM2CHRM1 | |
| SCHEMBL8042740 | 0.86 | DRD2 (0.48) | APPDRD2GRM3CHRM2CHRM1 | |
| SCHEMBL8039253 | 0.86 | ACACB (0.45) | ACACBKCNH2 | |
| SCHEMBL8045708 | 0.85 | FFAR1 (0.41) | CHRM2CHRM1ACACBKCNH2 | |
| SCHEMBL9512333 | 0.83 | DRD2 (0.49) | APPDRD2GRM3ACACBGRM2 | |
| SCHEMBL8040935 | 0.82 | ACACB (0.36) | ACACB | |
| SCHEMBL13621706 | 0.81 | DRD2 (0.50) | APPDRD2GRM3ACACB | |
| SCHEMBL5343187 | 0.81 | DRD2 (0.50) | APPDRD2GRM3ACACB | |
| SCHEMBL8046325 | 0.80 | SPHK1 (0.41) | ACACB | |
| SCHEMBL9512417 | 0.80 | MCHR1 (0.47) | APPDRD2GRM3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |